Exercises in Style was written by Raymond Queneau after years of writing the same inconsequential story of a confrontation on a bus and a chance second encounter in different styles. From blurbs to police reports, removing certain letters, and using only onomatopoeia, he ended up with 99 of them.
Matt Madden, inspired by Queneau, did the same thing with graphic novels. Taking the same inconsequential story and illustrating it in 99 different styles, from newspaper humour, to film noir, to monologue, to switching round the images.
(edit: I was recently asked to take part in a film work of the same nature, curse Vimeo's lack of email updates as I would have done it. 28/04/11)